Understand: This pillar focuses on understanding how the normal brain develops and functions, and how it evolves throughout a lifetime.

Address: This pillar focuses on translating fundamental new knowledge about the brain into new prevention strategies and treatments for brain disorders.

Apply: This pillar uses the new knowledge to inspire discovery in other fields, notably information and communication technology, economics, complex systems, ethics, human social behaviour and education.

Build: This pillar drives the development of new tools to visualize and measure the brain, computational techniques to understand its complexity, as well as brain-inspired technologies.